If you want a clue on the MOA of baclofen, add "GA" to the front of the name to make GAbaclofen. Baclofen is a GABA B agonist used for its muscle relaxing properties.
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21 hours ago
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just wanted to point out that Baclofen is a GABA B "antagonist" cause it inhibits those receptors at spinal cord level
ReplyDeleteNo, it is an agonist. GABA is an inhibitory transmitter, thus facilitating relaxation.
ReplyDeletehttps://en.wikipedia.org/wiki/Baclofen