The key to understanding heart murmurs is realizing that:
Systole=ventricle contracting
Diastole=atria contracting or the aortic pressure pushing back on the aortic valve
Murmurs that occur during SYSTOLE:
1. Blood going forward through a narrow aortic valve (aortic stenosis, crescendo-decrescendo)
2. Blood going forward through a ventricular septal defect (VSD, holosystolic)
3. Blood going through a narrowed aortic outflow tract (hypertrophic cardiomyopathy)
4. Blood going back through a leaky mitral valve (mitral regurgitation, holosystolic)
Murmurs that occur during DIASTOLE (remember that diastole is when the atria contract or the aorta pushes back on the aortic valve):
1. Blood going forward through a narrow mitral valve (mitral stenosis)
2. Blood being pushed back through a leaky aortic valve (aortic regurgitation)
The murmur of an atrial septal defect (ASD) is a fixed split S2.
Heart Murmurs
Labels:
Cardiology
A video is worth a thousand words.
Let's say you're having a tough time visualizing the fetal circulation in your head and diagrams just aren't cutting it. Google has a cool feature that allows you to search for Flash videos by using the filetype:swf modifier. For example if I wanted flash videos on the fetal circulation, I typed fetal circulation filetype:swf.
Here's a nice flash animation on the fetal circulation that I found with this Google search.
Labels:
Cardiology,
Embryology
Sloppy Joes!
Both HCV and HIV are sloppy reproducers, making their structure too variable to create a working vaccine against them.
Neisseria gonorrhea is usually tested on its highly variable pili, which makes it difficult to target with a vaccine.
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